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The reduction in calorie intake leads to weight loss which is generally substantial in the first few months

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Park D-D, Gahr BM, Krause J, Rottbauer W, Zeller T, Just S

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It may be stated that it acts as a neurotransmitter or neuromodulator on adjacent GLP-1R-expressing nerve fibers, enhancing attraction to sweet tastes and contributing to residual sweet perception even in the absence of T1R3 (65)