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Tirzepatide (Mounjaro/Zepbound) may cause slightly more GI side effects overall because it targets two receptors (GLP-1 + GIP), but individual responses vary

We recommend Semaglutide GLP-1 as part of your weight loss regimen only when lifestyle changes and other weight management strategies have not yielded the desired results

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Lifestyle changes, such as: Exercises Dietary changes Weight loss Stopping substance use These lifestyle modifications or changes can help you feel better

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The expected benefit and safety depend on the exact product and the individual patient