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HPLC analysis provides a chromatographic purity profile that identifies both the target peptide peak and any impurity peaks their ratio determines the reported purity percentage

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The latest move builds on the agency's decision in September to add semaglutide and tirzepatide, active ingredients in Novo Nordisk's Ozempic and Eli Lilly's Mounjaro, to its essential medicines list for managing type 2 diabetes in high-risk groups

doi: 10.1038/s41580-020-00324-8 76 ConradMSatoH