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Reconstituted solutions should be stored at 2 to 8 degrees Celsius, protected from light, and used within a short window

Those medications are part of a class of drugs called GLP-1s, and demand for the treatments has exploded in recent years

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Technical barriers during NP preparation also complicate scale-up and mass production of precisely engineered NPs, further increasing cost [136]

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Hence, a peptide was designed by substituting the negatively charged residues D42, D48, D49, E51, E56, and D57 within the p53 TAD PEP with alanine to increase its binding affinity to FOXO4 FHD and enhance membrane penetration