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doi:10.1016/S0021-9258(17)38940-8
Glutathione, often referred to as the mother of all antioxidants, is one of the most talked-about supplements in the healthcare industry
Disproportionality signals for IGE All five GLP-1RAs had statistically significant reporting odds ratios (RORs) for IGE: Semaglutide: ROR 24.8 Dulaglutide: ROR 14.7 Liraglutide: ROR 13.7 Exenatide: ROR 5.4 Tirzepatide: ROR 18.3 This analysis confirms that these drugs are significantly more likely to be reported in conjunction with IGE compared to other medications
O'Donnell, J., Finer, N
Key Takeaways Topamax is not FDA-approved for weight loss but is sometimes used off-label for this purpose
However, for women with compromised glutathione status (PCOS, IVF conception, gestational blood sugar issues, poor diet, environmental exposures), even therapeutic doses may generate toxic metabolites that affect fetal brain development
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