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The study began in December 2023 with estimated completion in May 2026 and is currently actively recruiting across multiple international sites, with Phase 1 healthy volunteer data showing favorable safety profile, dose-proportional pharmacokinetics with 2-week half-life, and approximately 50% reduction in PD-1 expressing CD4+ and CD8+ T cells lasting over 30 days, supporting progression to this Phase 2 efficacy trial (67)

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Wegovy is FDA approved for chronic weight management in adults and adolescents 12 years and older with obesity or adults with overweight and at least one weight-related medical condition

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10.1055/s-0035-1569330 35 DarabianS.HormuzM.LatifM

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Cost barriers She praised Medicares new GLP-1 Bridge Program, which lowers monthly costs for eligible beneficiaries to about $50 if their Part D plans do not already provide coverage

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Eligibility is based on BMI and health criteria, not cosmetic goals

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