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The health benefits of dietary polyphenols on pediatric intestinal diseases: Mechanism of action, clinical evidence and future research progress

Both the thioredoxin (Trx) and GSH-dependent glutaredoxin (Grx) antioxidant systems have been found to reduce methionine sulfoxide reductases in vitro and/or in vivo (see Figure 2 ) (28)

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No published human pharmacokinetic study demonstrates sufficient oral bioavailability of these unmodified peptides to produce the GH-releasing effects seen with injection

Diagnosis of deficiency and insufficiency clinical and laboratory pitfalls , Critical Reviews in Clinical Laboratory Sciences, DOI: 10.1080/10408363.2021.1885339 Thain A, et al