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Measuring myocyte oxidative stress and targeting cytokines to evaluate inflammatory response and cardiac repair after myocardial infarction

Because the availability of the amino acid cysteine is the primary rate-limiting bottleneck for natural glutathione production, flooding the system with NAC ensures the cellular assembly lines are fully stocked

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10.1111/j.1365-2621.2002.tb08778.x 178 van de MortelJ

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Interestingly, GSH deficiency upregulates genes associated with NAFLD (Fig