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doi: 10.1210/jc.2003-030421 38 WynneKParkAJSmallCJPattersonMEllisSMMurphyKGet al

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1 Introduction Type 2 diabetes mellitus, also called non-insulin-dependent diabetes mellitus, is a chronic metabolic disease characterized by high blood glucose levels, caused by beta cell dysfunction and insulin resistance, and the majority of patients are adults

Mechanistically, they directly promote hepatic glucose metabolism and reduce fat accumulation