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Serious Risks to Consider Tirzepatide carries additional FDA-required warnings: Thyroid C-cell tumor risk (based on rodent data) Gallbladder issues Acute pancreatitis Kidney injury (secondary to dehydration risks) Mazdutides trials showed very low serious adverse event rates
For example, in the study by Novinscak et al
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T et al
Reviewing previous IBD treatment response: If a biologic or advanced IBD treatment has not worked as expected, it may be appropriate to review treatment history, disease activity, drug levels, antibodies, timing of response and whether symptoms are due to inflammation or an overlapping condition