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However, excessive glucose concentrations can be detrimental, as demonstrated in studies showing metabolic stress responses in astrocytes exposed to high glucose levels

Coverslips were kept in the dark at RT for one night, then they were stored at 4 C

The metabolic reprogramming of CAFs thus represents a novel mechanism of immunotherapy resistance that can be targeted using nanoparticle-based approaches (35)

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This polymorphism has clinically significant interactions with MTHFR variants because both independently drain the SAM-e pool