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This finding suggests that the nutrient also affects melanin production in the hair follicles

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Oral formulations have a shorter half-life.[ref] In clinical trials, GLP-1 RAs improved lipid profiles, increased satiety, slowed gastric emptying, reduced inflammation, and had neuroprotective effects.[ref] The slowing of gastric emptying and reducing inflammation may play a role in weight loss, along with the decrease in appetite and eating less

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Retatrutide is a promising investigational agent, but its place in clinical practice and its full cardiovascular safety profile will only be established through rigorous, ongoing research