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The prevalence of side effects with regular and sustained-release nicotinic acid
Jayasena CN, Franks S
In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity, thereby protecting the cells from reactive oxygen species and the products of peroxidation
Any questions about what to expect should be discussed with your healthcare provider
Cells have developed a sophisticated antioxidant system to protect against these oxidative insults, consisting of enzymes that either convert superoxide radicals into hydrogen peroxide (H 2 O 2 , SOD1, and catalases) or H 2 O 2 into water and oxygen [peroxiredoxin (Prx) and glutathione peroxidase (GPx)
A more detailed discussion of safety and tolerability are provided later
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