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Can Wegovy be used intermittently, or does it require continuous use
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Mild nausea, appetite suppression, and gastrointestinal adjustments are common initially and typically resolve as your body adapts
This diagnostic difficulty contributes to later presentation and, on average, a greater Breslow thickness at excision
Why Brand-Name Cant Match Price Structural Barriers: Public Company Obligations: Must maximize shareholder return Quarterly earnings pressure Executive compensation tied to profits Cant dramatically reduce price without stock impact Sunk Costs: Billions invested in development Need to recoup investment Justify to shareholders and board Complex Distribution System: PBMs demand rebates Wholesalers take cut Pharmacy margins Cant easily change system Market Dynamics: Limited competition (patent protection) Can charge premium prices Demand exceeds supply No pressure to reduce Eli Lilly unlikely to reduce tirzepatide prices significantly while patents protected
Glycemic Control: Significant reductions in HbA1c (12%) in type 2 diabetes patients
