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320 Moreover, resistance to cancer therapy has been attributed to the self-renewal and dedifferentiation of cancer stem cells (CSCs) residing within the tumor

These medications work by mimicking the effects of GLP-1 in the body, leading to enhanced insulin secretion, reduced glucagon production, and increased satiety, thereby improving blood sugar control and promoting weight loss

Ozempic has proven to be so effective in helping with weight management that its manufacturer was unable to keep up with demand and pharmacies and insurers encouraged its use be restricted solely to the treatment of diabetes

Typical dosing starts low and gradually increases to reduce nausea and other gastrointestinal discomfort, though discontinuation still occurs in a notable portion of users

CrossRef Genetic susceptibility of Iraqis for obesity and type 2 diabetes: LEPR gene polymorphisms Maysoon K

However, both substances independently affect blood glucose regulation and gastrointestinal function, creating physiological risks that require clinical consideration