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Gastric bypass surgery : This surgery alters the digestive system, reducing the bodys ability to absorb B12 from food and supplements.For these individuals, methylcobalamin B12 injections provide a direct way to bypass the digestive system and restore essential B12 levels

Used in apoptosis pathway studies, p53-FOXO4 interaction research, and senescent cell clearance investigations

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It was found that the expression of PLC-4 gene in this pathway decreased in cancer, but there was no significant difference in Wnt5a mRNA level