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Given the shared neuropathology, clinical presentation, and risk factors between DS and AD, their cognitive profiles also exhibit similarities

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Presented for research literature review only Reed DJ (1990)

[36] [37] [38] LS is a very rare condition with a total of 250 known individuals worldwide

Doi: Moldrich RX, Lain J, Visel A, Beart PM, Laffaire J, Rossier J, Potier MC (2008) Transmembrane Protein 50b (C21orf4), a Candidate for Down Syndrome Neurophenotypes, Encodes an Intracellular Membrane Protein Expressed in the Rodent Brain

For patients who have done the work on diet and exercise and still carry clinically significant visceral fat, it represents one of the few pharmacological tools with both the mechanism and the data to address the problem directly