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Why wouldnt you treat what youre tracking
It arrived in a cold pack
Means lower Emerging observational studies and small interventional trials suggest that GLP-1 RAs may be used in patients with advanced CKD with preserved glucose-lowering efficacy and a relatively low intrinsic risk of hypoglycemia compared with insulin and sulfonylureas (1823)
That matters because tolerability tracks the size of the swing during starts, dose jumps, missed doses and restarts, while at stable maintenance it tracks average concentration which splitting leaves unchanged by design
Sourcing matters: Poor-quality versions exist
J Neuropathol Exp Neurol 44(4):397403
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