Ratliff J, Leite JO, de Ogburn R, Puglisi MJ, VanHeest J, Fernandez ML
The treatment is part of a holistic medical weight management strategy, which includes lifestyle and dietary modifications to maximize the effectiveness of the medication and support long-term health improvement
Medications that may be considered are estradiol, micronized progesterone, and thyroid replacement if necessary
GLP-1 patients may need to adjust their expectations, adhere more closely to treatment or opt for metabolic and bariatric surgery to achieve desired results. The study was a retrospective comparative effectiveness study using the real-world electronic medical record data of NYU Langone Health and NYC Health + Hospitals patients with a body mass index (BMI) of at least 35 who had bariatric surgery (sleeve gastrectomy or Roux en-Y gastric bypass) or were prescribed injectable semaglutide or tirzepatide between 2018 and 2024
One randomized controlled trial involving 60 subjects aged 60 years and older found baseline sleep quality, based on PSQI scores, among participants was poor and improved more in those receiving 200 mg chamomile extract twice daily for 28 days than placebo
GLP-1 agonist drugs such as semaglutide (Ozempic TM and Wegovy TM ) and tirzepatide (Mounjaro TM ) were initially developed to mimic this hormone and treat type 2 diabetes (T2D)