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Table 16 for Study 7, and in Table 17 for Studies 8 and 9
(Migraines are considered chronic when someone has a headache on 15 or more days a month for at least three months.) The researchers divided the participants into two groups: Those who started taking a GLP-1 medication for another condition (such as type 2 diabetes or obesity) within a year of being diagnosed with chronic migraines, and those who started taking topiramate (a prescription medication used to prevent migraine headaches) during the same period
It is also abundant in the gastrointestinal system and in the pancreas, further enhancing a calming and deep sleep affect
This review synthesizes evidence from about 120 preclinical/clinical studies sourced from PubMed, Scopus, and Web of Science using keywords (e.g., nutraceutical-drug interactions, bioavailability, CYP/P-gp modulation), prioritizing recent advances (20152024) alongside seminal works to contextualize mechanisms
Asada et al
As a result, they reduce postprandial glucose spikes and improve overall glycemic control
