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The takeaway: While you cant keep taking GLP-1s, you have good options
AOD9604 vs Intact hGH in Obesity Models A direct head-to-head comparison of AOD9604 and intact hGH in obese and lean mice confirmed that both compounds significantly reduced body weight gain in obese animals through increased fat oxidation and lipolysis stimulation but that AOD9604 achieved this without the hGH receptor binding, IGF-1 stimulation, hyperglycaemia, or reduced insulin secretion associated with full-length hGH treatment
Instead of simply suppressing appetite like earlier drugs, it appears to increase energy expenditure, improve fat metabolism, and sustain significant weight loss over time
The Timing of Activity after Eating Affects the Glycaemic Response of Healthy Adults: A Randomised Controlled Trial
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10.1016/j.molmet.2016.09.005 23 FosgerauK.HoffmannT
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