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KaplanMeier curves demonstrated early and progressive separation, with 5-year cancer-free survival of 99.02% versus 98.81% (Fig

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Abbreviations APC: Adenomatous polyposis coli CDK5RAP2: Cyclin-dependent kinase 5-related activator protein 2 EB1: End-binding protein-1 ERK: Extracellular signal-regulated kinase CLASP: Cytoplasmic linker protein (CLIP)-associated protein FAK: Focal adhesion kinase GCP: -tubulin complex protein GSK-3: Glucogen synthase kinase-3 ILK: Integrin-linked kinase IQGAP: IQ motif-containing GTPase-activating protein KANK: KN motif and ankyrin-repeat-containing protein KIF21A: Kinesin family member 21A LL5: Pleckstrin homology-like domain family B member 2 mDIA: Diaphanous-related formin-1 MMP: Matrix metalloproteinase MOZART: Mitotic spindle organizing protein associated with a ring of -tubulin NEDD1: Neural precursor cell expressed, developmentally down-regulated-protein 1 PAK: p21-activated kinase PAR6: Partitioning-defective-6 PKC: Protein kinase C RSK2: Ribosomal-S6 kinase-2 References Hynes RO (2002) Integrins: bidirectional, allosteric signaling machines