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At their core, free radicals are unstable atoms or molecules with an unpaired electron
The estimated treatment difference is therefore 20.4 points under the trial product estimand and 17.3 under treatment policy: a gap of roughly 3.1 points on the effect estimate, not 2.3
The high levels of GSH, associated with the downregulation of GSS and increased G6PD expression, which is the main source of NADPH, is an indicator of a switch from GSH synthesis to glutathione recycling
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