Mena, S., Ortega, A., & Estrela, J
C-D, Heatmaps of upregulated (A) or downregulated (B) genes in the three RNAseq biological repetitions (1,2,3) before and after high temperature shift
Homocysteine rises when there is not enough B12 in the cell fluid to support methylation, an important process where a methyl group is added to all sorts of molecules in the cell
When glutathione production drops, you are more vulnerable to: autoimmune disease chemical sensitivities heavy metal sensitivities inflammatory disorders intestinal permeability (leaky gut) other immune issues Stress lowers glutathione levels When we are healthy, our bodies make enough glutathione to protect us
Research has confirmed that DPP4 can limit GSH levels, elevate lipid ROS, and ultimately lead to ferroptosis (6466)
NRF1 is a transcription factor that belongs to the same transcription factor family as NRF2