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Group Based Trajectory models (GBTM) were used to explore various patterns of progression of eGFR over duration of follow up in each of the main five ethnic groups

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Diabetes Care (2017) 40:11724

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[115] described that phosphoglycerate dehydrogenase (PHGDH), involved in the synthesis of serine and glycine from glucose, is critical for pancreatic tumor cells proliferation and tumorigenesis, mediating cell-tight junctions formation, mTOR activation (through Akt), and protein expression and translation, after interaction with the translation initiation factors eIF4A1 and eIF4E (which seems to be independent of its enzymatic activity)

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