GLP-1 medications don't require a special amount of water, but they quietly cut your water consumption if you're not paying attention: they blunt appetite and thirst cues, slow how fast your stomach empties so you feel full sooner, and can cause fluid loss through nausea or diarrhea
doi:10.1093/jnci/djj494 Drucker DJ
A medicine supply notification issued by the Department of Health and Social Care on 27 June 2023 said the high impact shortage has been caused by an increase in demand for these products for licensed and off-label indications, with supply not expected to return to normal until at least mid-2024
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Rorth R, Jhund PS, Mogensen UM, Kristensen SL, Petrie MC, Kober L, McMurray JJV
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