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Briefly, approximately 1520 DP were cultured per a 60 mm dish in 5 ml of Dulbecco's modified Eagle's medium (DMEM

4.1 The role of immune cells in the local microenvironment of OA Macrophages are among the most prominent immune cells within the OA synovium

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: Different mechanisms

Concentrations naturally decline with age (from about 200 ng/mL at age 20 to 80 ng/mL by age 60), which is part of why supplementation makes sense