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While the liver is qualitatively critical for glucose metabolism, skeletal muscle is quantitatively essential since skeletal muscle accounts for 35%45% of body weight and up to 70%80% of total glucose disposal after insulin stimulation

From the perspective of an organic chemist, peptide synthesis requires selective acylation of a free amine

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Coogan AN, Thome J

Xu LX, Xuan HW, He W, Zhang L, Huang MY, Li K, et al