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Repetitive elements are normally subject to tight genomic regulation through multiple mechanisms, including epigenetic repression (DNA methylation and histone modification), RNA interference (RNAi), repeat-binding protein complexes, and genome stability systems such as those acting at telomeres (Wallrath et al., 2022)

Lixisenatide is also a key ingredient in the diabetes drug Soliqua, which is available in the US

Long-term human safety data for both compounds is limited

This week on Gadget Lab, we talk with WIRED writers Kate Knibbs and Emily Mullin about how GLP-1 medications like Ozempic work and what happens when they dont

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