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Patients with variants linked to lower GLP-1 receptor expression may benefit from consistent, predictable dosing schedules that allow the medication to accumulate over weeks, while those with high-sensitivity variants often feel effects more rapidly after each injection
It gained considerable attention when the FDA approved its use to help obese and overweight patients reduce their risk of major adverse cardiovascular events, and Medicare even announced it would start covering semaglutide, a step previously unseen when it came to obesity medications
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But since the FDA declared the shortage over last year, companies that offer compounded drugs are increasingly facing legal and regulatory challenges related to their marketing tactics
