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Your Brain Shrinks During Dehydration (And Yes, You Can Feel It) When you're dehydrated, your brain tissue temporarily shrinks, pulling away from your skull

10.1016/S0006-291X(02)00430-8 175 NaharL.CharoensupR.KalievaK.HabibiE.GuoM.WangD.et al (2025)

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As a general procedure, the investigators directly performing the experimental procedures were not blinded to the group allocation, but data analyses by senior authors were largely conducted independently to avoid potential bias