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doi: 10.2337/diabetes.52.7.1786 121 FehseFTrautmannMHolstJJHalsethAENanayakkaraNNielsenLLet al
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A multicenter observational study in Japan published in the Frontiers in Clinical Diabetes and Healthcare found that individuals with type 2 diabetes taking glucagon-like peptide-1 receptor agonists (GLP-1RAs) showed reduced external eating scores after 12 months of therapy Their blood sugar levels, body weight, and body fat percentage also decreased significantly Emotional and restrained eating showed only transient changes
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Therefore, inhibition of GSK3 reduces the expression of BACE-1 gene and reduces amyloid burden and associated inflammation (Fronza et al
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