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Increased Angiogenesis : The peptide stimulates angiogenesisthe formation of new blood vesselsthrough the upregulation of vascular endothelial growth factor (VEGF)

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This represents an early stage of conventional necrosis, may occur within hours after exposure to a xenobiotic, and should not be diagnosed as single cell necrosis (apoptosis)

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Oxidative stress and mitochondrial dysfunction Mitochondria are not only the primary site of ROS production but also major targets of oxidative stress