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PMID: 41796712 References are provided for research reference only

FDA approval wont happen until all necessary trials complete

No dose reductions or treatment discontinuation due to toxicity were needed in the HER2 -mutant cohort [24]

Recent reports indicate that the reverse Warburg effect may also occur in the tumor formation process, whereby tumor cells undergo oxidative phosphorylation (OXPHOS) instead of glycolysis (221)

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However, research suggests that weight loss tends to be faster and more significant on higher doses of the drug