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It also affects metabolic pathways, nutrient uptake, and cellular regeneration in experimental models

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The risk of clinical manifestations had a slight upward trend in the presence of the A allele of the rs8177179 polymorphism, however without statistical significance

Indeed, with respect to diabetes, several mitochondrial diseases manifest with diabetic complications such as mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) and maternally inherited diabetes and deafness (MIDD)

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