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N Engl J Med 383:14361446
El contenido de agua no debe exceder el 1.0%
This is primarily because (1) both energy metabolism and production of oxidants are enhanced during exercise, and (2) creatine participates in ATP turnover in skeletal muscle and is a potent antioxidant
The pharmaceutical industry continues developing even longer-acting formulations
Serious adverse effects are rare but occur at a higher rate than with placebo
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