C.Zia Ul Haq KatshuM.LiddleP
Vidal-Vanaclocha, F
Do GLP-1-based therapies increase cancer risk
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GLP-1s support weight loss by: Delaying gastric emptying, which helps you feel fuller for longer after meals Regulating blood sugar, which can support steady energy and fewer cravings Reducing appetite and food noise by acting on hunger-regulating areas of the brain While Ozempic, Wegovy, Foundayo, and Zepbound all fall under the GLP-1 umbrella, Zepbound is unique in that it also targets another hormone called GIP (glucose-dependent insulinotropic polypeptide)
TRIUMPH-4, the first Phase 3 obesity readout (Dec 2025), reported about 28.7% mean weight loss at the top dose at 76 weeks the largest figure seen in any GLP-class trial so far