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Data will be used to support NIH-level grant proposals to examine suvorexant for this indication in a large, randomized trial

Although there is hypokalemia in Liddle syndrome the use of the aldosterone antagonist, spironolactone, has no therapeutic benefit due to the fact that aldosterone levels are normal to low

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Assuming that there are 24 million individuals treated with AOM by 2035 and that on average people lose 17.5% of their body weight, we estimate a 1.3% reduction in calories consumed relative to the status quo