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[10] Synergy is observed when tretinoins barrier-disruptive effect is offset by niacinamide-induced ceramide synthesis, allowing maintenance of retinoid efficacy with fewer erythema and peeling events
TB-500 Maintenance: 1,250 mcg once weekly for Weeks 512
Moisturize and Hydrate: Apply a soothing moisturizer to nourish the skin and reduce dryness or flaking
An estimated 50-75% of users stop taking these drugs within a year
10.1016/0378-1119(89)90377-6 Gene 48 MutallipM.NohataN.HanazawaT.KikkawaN.HoriguchiS.FujimuraL.et al (2011)
It can pass through the gastrointestinal environment and participate in normal physiological processes related to antioxidant activity and cellular balance
