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Although a small observational pilot study on 15 diabetic patients with biopsy-proven NAFLD demonstrated biochemical and histological improvement after a 1-year course of sitagliptin [89] further RCTs failed to demonstrate any beneficial effect of sitagliptin on NAFLD in diabetic patients

Becker et al., 2009a)

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Gerwien H, Hermann S, Zhang X, Korpos E, Song J, Kopka K, et al

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Casey Mulligan, a University of Chicago economist, estimated that PBMs create $145 billion in annual net economic benefit via consumer savings from reduced brand prices, increased generic usage, better health outcomes from increased access to pharmaceuticals, a faster pace of drug development, and government savings on subsidies for premiums in Medicare and other federal drug programs