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Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration

Effects of non-steroidal anti-inflammatory drugs (NSAIDs) and gastroprotective NSAIDs on the gastrointestinal tract: a narrative review

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Stable for 24+ months

(PubMed) Pan X, Sang S, Fei G, et al

Collectively, these studies firmly confirm that iron chelators represented by DFO alleviate DR pathogenesis by regulating iron homeostasis and inhibiting oxidative stress and inflammation, and the FDA-approved clinical status of DFO further solidifies the translational feasibility of iron chelation therapy