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A six-month treatment with exenatide, a short-acting GLP-1R agonists, was evaluated in a longitudinal study on 10 overweight/obese patients with PWS3 patients were affected by T2Dshowing a reduction in appetite scores and an improvement in HbA1c, with no changes in weight or BMI [100]
In terms of renal effects, the evidence of SGLT2is in preventing kidney failure is more abundant than for GLP-1RAs, which showed a beneficial effect on albuminuria and not on hard kidney endpoints [3, 6, 8]
May 2022;8(3):1025-1035
Kannt A, Rajagopal S, Kadnur SV, et al
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