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Phosphorylation of acetyl-CoA carboxylase by AMPK reduces renal fibrosis and is essential for the anti-fibrotic effect of metformin
Scirica BM, Bhatt DL, Braunwald E, Steg PG, Davidson J, Hirshberg B, Ohman P, Frederich R, Wiviott SD, Hoffman EB, Cavender MA, Udell JA, Desai NR, Mosenzon O, McGuire DK, Ray KK, Leiter LA, Raz I: SAVOR-TIMI 53 Steering Committee and Investigators
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Some observational studies and case reports have documented instances of pancreatitis and, less commonly, pancreatic cancer in patients taking GLP-1 receptor agonists
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