Patients taking certain medications (e.g., chloramphenicol may reduce the effectiveness of B12 therapy) or with risk factors for B12 deficiency (metformin use, proton pump inhibitors, nitrous oxide exposure, vegan diet) should discuss these with their healthcare provider
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If you are mildly B12 deficient but are otherwise in good health, you may be able to raise your B12 levels with a few simple dietary adjustments