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Aquaporin 4 as a NH3 Channel
Lee et al., 2011
However, up to 10% undergoes bioactivation to N -acetyl p -benzoquinone imine (NAPQI), a highly reactive electrophile, which is known to covalently bind to nucleophilic centers, including cysteine thiols in liver proteins (see Figure 1) (Jollow et al., 2015)
Faseb J 17(9):1553
To be considered legally intoxicated in the United States, a persons BAC would be at or above 0.08%
Antitumor properties of triptolide: phenotype regulation of macrophage differentiation
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