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Drug working concentrations and stock preparation were as follows: GLP-1MK-801 and MK-801 (both 50 M, dissolved in aCSF or magnesium-free aCSF), NMDA (100 M, dissolved in magnesium free aCSF), CNQX (10 M, dissolved in DMSO, Alomone Labs), picrotoxin (100 M, dissolved in DMSO)

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An intramuscular injection (commonly 1,000 mcg , given in the upper arm, hip or thigh) sidesteps the gut entirely and delivers a near-complete dose into circulation within minutes

This is especially important with compounded medications, which may have different stability profiles than their brand-name counterparts

While Wegovy can help lower blood sugar levels over time, it does not quickly lower blood sugar like insulin