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It helps transport long-chain fatty acids into the mitochondria, where they are converted into energy, making it essential for energy production, endurance, and overall metabolic health

BMJ 338:b496

Among the mutations considered, Glu113Lys enhanced catalytic performance and was added to X(GD_L)dX(GD_L)f to yield X(GD_L)gX(GD_L)i

201 In breast cancer, elevated HSP90 levels stabilize estrogen receptor (ErbB)-dependent PI3K/AKT and ERK signaling pathways, counteracting the effects of hormonal therapies such as fulvestrant

thus, plasma membrane-associated DPP4-mediated lipid peroxidation is prevented, and ferroptosis is inhibited (Fig