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Acknowledgements The authors would like to acknowledge the invaluable support and contributions of Kiko Wemmer, Man Qing Liang and Jamie Dermon, MD in developing this study and manuscript.
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Investigational means that its still in the research phase and is not approved by the U.S
[13] [15] There is a risk of oxalate nephropathy or kidney stone formation, particularly in patients with pre-existing renal impairment or those receiving prolonged high-dose therapy
Nausea, diarrhea, and vomiting most common
Inside cells, the enzyme glutathione reductase (using NADPH as a cofactor) continuously regenerates GSH from GSSG, maintaining a GSH:GSSG ratio of approximately 100:1 under healthy conditions
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