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As people age, they sometimes have trouble absorbing vitamin B12, even when taking pills by mouth, which is when vitamin B12 injections may be considered
When a cell over-expresses NNMT, it does two costly things at once: it burns through methyl-donor capacity, and it diverts nicotinamide away from NAD+ regeneration into an inert metabolite (1-methylnicotinamide) that gets excreted
One survey found that over 60% of medical providers offer B12-vitamin Shots to their patients
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Nature Chemical Biology
Pilitsi, E
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