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The standard eligibility criteria require either a BMI of 30 or higher, or a BMI of 27 or higher combined with at least one weight-related health condition

Am J Physiol Renal Physiol (2011) 300:F11421151

Patients often report significant weight loss and improved blood sugar control

These bands of fibrous tissue are important sites for storing and metabolizing glucose or for burning it for energy

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For a broader view of how these newer agents compare, the semaglutide vs tirzepatide comparison page offers a useful starting point